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Prostaphil-2 - AOR

Prostaphil-2 - AOR Prostaphil-2 is a superior, natural, treatment for many prostate problems including BPH. This unique formula relieves symptoms & treats the root cause without side effects.
$39.00 90 veg capsules/bottle
NPN # 80045408
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Key Benefits at a Glance:

  • Reduces prostate volume
  • Relieves symptoms of benign prostate hyperplasia
  • Reduces inflammation

Product Description:

Prostaphil-2 is defined pollen extract, which is not bee pollen, but a defined blend of water and fat-soluble extracts from specific pollens in characteristic ratios first crafted in Sweden. Research demonstrates defined pollen extract’s superior support for prostate health compared to saw palmetto and other common prostate herbals.

Defined pollen extract has been effectively helping European men with many prostate health problems for decades now, and is proven to do what no other herbal can: shrink swollen prostates. While relatively new in North America, defined pollen extract has been successfully used in Europe for two generations, and clinical trials have proven its superiority to other prostate supplements. As the pollen itself is golden, so defined pollen extract may open up a golden age for safe, natural therapy for the most personal of male health concerns. AOR’s Prostaphil-2 provides an exciting solution for prostate problems.

BPH: A Real Pain in the Prostate

Benign prostate hyperplasia (BPH) is a nonmalignant welling of the prostate gland that affects the majority of men beginning in late middle age. The swelling constricts the urethral opening and leads to discomfort, frequent and sudden urges to urinate, and incomplete bladder emptying. While other herbals improve these symptoms, they do not deal with the underlying problem of prostate swelling. This symptom relief can cause worse problems if men put off surgery and develop complications later on.

Pollen Potential

Prostaphil-2 is a defined pollen extract; not bee pollen but a defined blend of extracts from specific pollen fractions. Defined pollen extracts not only improve BPH symptoms, but also reduce the volume of the prostate, thereby fixing the problem, not concealing it.

Defined pollen extract reduces inflammation and balances muscle tone in the urethra and bladder, and studies suggest it may help with detoxification and liver protection.

A Superior Solution

While relatively new in North America, defined pollen extract has been successfully used in Europe for two generations, and clinical trials have proven its superiority to other prostate supplements. AOR’s Prostaphil-2 provides an exciting solution for prostate problems.

Benign prostatic hyperplasia (BPH) – the noncancerous swelling of the prostate gland, leading to discomfort, nocturia (the need to get up in the middle of the night for a trip to the bathroom), frequent and sudden urges to urinate even when the bladder is not full, intermittency, and incomplete emptying of the bladder when urinating – affects nearly all men to some degree beginning in late middle age.

Saw palmetto and other herbals improve the symptoms of BPH without addressing the fundamental problem: the actual increase in volume of the prostate gland itself. Experience with drugs which relieve BPH symptoms without addressing prostate size has shown that, lacking any warning symptoms, men often put off surgery for far too long, leading to concern that these treatments may actually increase the complications of BPH.

The Real Prostate Health Alternative

Defined pollen extract is different. While still new to Canadians, defined pollen extract has been used with success by two generations of European men. Defined pollen extract is not bee pollen. Bee pollen is a mixture of whatever pollens the insects happen to have come into contact with. Defined pollen extract, by contrast, is a mixture of several specific pollen sources (primarily rye, but also including timothy grass, corn, hazel, sallow, aspen, oxye, and pine pollens).

Proven in Controlled Trials

Four randomized, double-blind, controlled clinical trials have shown that defined pollen extract quickly improves BPH symptoms and reduces prostate volume. In one of these studies, sixty men with symptomatic BPH received either the pollen extract or placebo for six months. Sixty-nine percent of men receiving the pollen extract experienced improved overall symptoms, compared to less than a third of the placebo group. There were statistically significant differences in the number of incidences of nocturia and decreased leftover urine in the bladder after urination (“residual urine volume”). Most importantly, men using defined pollen extract experienced significant reductions in the volume of the prostate as measured by ultrasound. In fact, every trial of defined pollen extract in men with BPH, which has measured prostate volume, size, or weight has reported significant reductions in the gland.

Other Prostate Health Concerns

BPH, of course, is not the only prostate disorder that men may face. Others include chronic prostatitis (CP) and prostatodynia. Although the symptoms of these disorders sound similar, there is no evidence that saw palmetto or the other common herbals for BPH are helpful for these conditions. By contrast, several open trials have found that defined pollen extract is helpful in chronic prostatitis and prostatodynia.

Hope for Prostate Cancer

An even graver prostate health concern for many men is prostate cancer. Autopsy studies show that 15 to 30 percent of men over 50, and 60 to 70 percent of men over the age of 80, have latent, undiagnosed prostate cancer. Studies in isolated prostate cancer cells have found that fractions of the pollen extract selectively inhibit the growth of human prostate cancer cells. Defined pollen extract also lowers prostate specific antigen (PSA), considered a marker of prostate cancer risk. The reduction in PSA does not itself guarantee a corresponding reduction in risk; however, the results are certainly promising.

How Does it Work?

The mechanism of action of defined pollen extract remains elusive. Studies suggest that defined pollen extract may reduce inflammation and balance the muscle tone of the urethra and bladder – effects which might help to explain some of the extract’s effects on the symptoms of BPH.

But the exact method by which the defined pollen extract exerts its ability to reduce the actual volume of the prostate remains unknown. In test-tube studies, defined pollen extracts inhibit the enzyme which converts testosterone into the much more prostate-stimulating dihydrotestosterone (DHT); however, they also inhibit enzymes which convert DHT to less harmful metabolites. In other words, the pollen extract directly decreases both the synthesis and the clearance of DHT.

Further studies are clearly needed. All we can say with certainty, from existing evidence, is that defined pollen extract works, relieving the symptoms of BPH and reducing prostate volume. How it works is a question for continued scientific investigation.

Research

Proven in Controlled Trials - In one study, sixty men with symptomatic BPH received either the pollen extract or placebo for six months. Sixty-nine percent of men receiving the pollen extract experienced improved overall symptoms, compared to less than a third of the placebo group. There were statistically significant differences in the number of incidences of nocturia, decreased leftover urine in the bladder after urination (“residual urine volume”). Compared to the placebo group, there were also more improvements reported by men receiving the pollen extract in hesitancy (inability to release urinary flow) and intermittency, but these results were not strong enough, in this small a group over this short a period, to be statistically meaningful.

But most importantly, this study reported that men using defined pollen extract experience significant reductions in the volume of the prostate as measured by ultrasound. In fact, every trial of defined pollen extract in men with BPH, which has measured prostate volume, size, or weight has reported significant reductions in the gland.

Not Just for the Prostate… And Not Just for Men!

Most people taking the pollen extract are using it for the health of their prostate, which is by far the best-backed usage for this botanical. Yet there are hints in the literature of a broad range of other applications which get much less attention. One such property is detoxification and hepatoprotection. Animal studies have found that the defined pollen extract provides protection against a variety of liver toxins, including as ammonium fluoride, paracetamol, organic solvents, allyl alcohol, the deadly carbon tetrachloride, cadmium, and galactosamine.

Finally, although we emphasize that the evidence is purely anecdotal, in some parts of the world more women buy defined pollen extracts than men, because they have found that the pollen extract helps with urinary incontinence – which, although unproven by clinical trials, is consistent with the improved bladder and urethral smooth muscle tone balance, which the pollen extract is known to afford. Funding is presently being sought to run a controlled trial on this application.

Supplement Facts:

Serving Size: 1 Veg. Capsule

Prostaphil-2 ............................ 126 mg

   Defined Pollen Extract † (1.7-3.7:1) 46 mg

Non-Medicinal Ingredients: microcrystalline cellulose, calcium hydrogen phosphate dihydrate, calcium gluconate, silicon dioxide, maltodextrin. Capsule: hypromellose. Prostaphil-2™ is a trademark of Pfannenschmidt Ltd.
Note: Herbal extracts will naturally vary in color from one batch to another.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Suggested Dose and Usage:

Take 1 capsule three times daily with or without food, or as directed by a qualified health care practitioner. Use for a minimum of 12 weeks to see beneficial effects.

Warnings And Contraindications:

While it has never been reported, allergic reactions to the pollen extract are theoretically possible. Allergic persons should consult a physician prior to use.

Pregnancy/Nursing: Consult a health care practitioner

Additional Learning And Information:

  1. Superior Prostate Support (from AOR)
  2. Prostaphil-2 And Saw Palmetto : A Comparison (from AOR)

 

Statements about these products and health conditions have not been evaluated by Health Canada or the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent disease. For the Complete disclosure statement click here.

References:
1.    Becker H, Ebeling L. Phytotherapy of BPH with cernilton N – results of a controlled prospective study. Urologe (B) 1991; 31: 113-6.
2.    Blumenthal M (ed). The Complete German Commission E Monographs. Therapeutic Guide to Herbal Medicines. Austin, TX: American Botanical Council, 1998.
3.    Brauer H. The treatment of benign prostatic hyperplasia with phytopharmata: a comparative study of cernilton vs. beta-sitosterol. Therapiewoche. 1986; 36: 1686-96.
4.    Buck AC, Cox R, Rees RW, Ebeling L, John A. Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study. Br J Urol. 1990 Oct; 66(4): 398-404.
5.    Dutkiewicz S. Usefulness of Cernilton in the treatment of benign prostatic hyperplasia. Int Urol Nephrol. 1996; 28(1): 49-53.
6.    Ebeling L. Therapeutic results of defined pollen-extract in patients with chronic prostatis or BPH accompanied by chronic prostatitis. In , Schmiedt E, Alken JE, Bauer HW (eds). Therapy of Prostatitis. Munich: Zuckerschwerdt Verlag, 1986; 154-60.
7.    Jaton JC, Roulin K, Rose K, Sirotnak FM, Lewenstein A, Brunner G, Fankhauser CP, Burger U. The secalosides, novel tumor cell growth inhibitory glycosides from a pollen extract. J Nat Prod. 1997 Apr; 60(4): 356-60.
8.    Maekawa M, Kishimoto T, Yasumoto R, Wada S, Harada T, Ohara T, Okajima E, Hirao Y, Ohzono S, Shimada K, et al. Clinical evaluation of cernilton on benign prostatic hypertrophy – a multiple center double-blind study with Paraprost. Hinyokika Kiyo. 1990 Apr; 36(4): 495-516.
9.    Roberts KP, Iyer RA, Prasad G, Liu LT, Lind RE, Hanna PE. Cyclic hydroxamic acid inhibitors of prostate cancer cell growth: selectivity and structure activity relationships. Prostate. 1998 Feb 1; 34(2): 92-9.
10.    Yasumoto R, Kawanishi H, Tsujino T, Tsujita M, Nishisaka N, Horii A, Kishimoto T. Clinical evaluation of long-term treatment using cernitin pollen extract in patients with benign prostatic hyperplasia. Clin Ther. 1995 Jan-Feb; 17(1): 82-7.
11.    Zhang X, Habib FK, Ross M, Burger U, Lewenstein A, Rose K, Jaton JC. Isolation and characterization of a cyclic hydroxamic acid from a pollen extract, which inhibits cancerous cell growth in vitro. J Med Chem. 1995 Feb 17; 38(4): 735-8.

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